Historical canvas paintings are subject to many destructions due to their age. Among these damages, environmental pollution such as moisture, light, atmospheric pollution, biological pollution and vandalism can be mentioned. The settling of SO2 and SO3 gases in the air next to the humidity on the paintings causes acidification of the canvas, which in addition to weakening the support of the painting, weakens the connections of the paint to the underlying layer and ultimately results in the deterioration of the work. Therefore, deacidification of painting canvas will be a serious and very effective measure to prevent the destruction of the work. The traditional methods of deacidification, which have been used until today, unfortunately left adverse effects on the work, such as dandruff and weighting of the painting fabric. With the advancement of technology and nanotechnology, new methods have been presented for deacidification of historical works, including cloth, wood and paper. The use of calcium hydroxide nanoparticles makes it possible to spray materials in restoration operations. Due to the small size of nanoparticles and the lack of concentration of solutes on the surface of the effect and the high penetration depth due to the ability of nanoparticles to be absorbed by cotton fibers, it causes the high efficiency of nanoparticles compared to coarse particles. In this article, firstly, the use of calcium hydroxide nanoparticles in deacidification of canvas painting canvas is investigated, then the methods and method of calcium hydroxide nanoparticle production, its stability and lifespan are discussed.