The most important part of the archives of libraries and museums of each country are the historical papers that can be damage by various factors. Chemical damaging agents of paper such as oxidation and acidic hydrolysis effects have always been a major challenge for refiners and researchers in the field. Nanotechnology is one of the most effective and innovative tools to reduce the rate of degradation. In this study, we tried to use titanium oxide/zinc oxide/cationic starch nanocomposite to prevent the oxidation process. For this purpose, titanium oxide/zinc oxide nanocomposite as well as cationic starch were applied. Herein, in addition to stopping the oxidation process, de-acidification and consolidation were also observed at the same time. Also, in this method by several steps were combined in a single step that could be led to saving in the material consumption and time. Various instrumental analysis such as infrared spectroscopy, electron microscopy images, paper tensile strength measurements and accelerated thermal aging were used to investigate the chemical and physical properties. The results showed that the coating of paper with titanium oxide/zinc oxide/cationic starch nanocomposite in compare with titanium oxide/ zinc oxide nanocomposite and cationic starch was more effective and approved as an antioxidant agent.